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Oxidative stress in Ca2+-induced membrane permeability transition in brain mitochondria
(Blackwell Publishing LtdOxfordInglaterra, 2001)
Drug-induced mitochondrial dysfunction and neurotoxicity
(Nova Science Publishers, 2019)
Mitochondria exerts numerous physiological functions such as energy production and maintainance of calcium homeostasis. The brain is a tissue highly dependent on energy production; 20% of total oxygen consumption is used ...
Hypoxia induces complex I inhibition and ultrastructural damage by increasing mitochondrial nitric oxide in developing CNS
(Wiley Blackwell Publishing, Inc, 2008-12)
NO-mediated toxicity contributes to neuronal damage after hypoxia; however, the molecular mechanisms involved are still a matter of controversy. Since mitochondria play a key role in signalling neuronal death, we aimed to ...
Mitochondrial function in spinal cord injury and regeneration
(SPRINGER BASEL AG, 2022)
Many people around the world suffer from some form of paralysis caused by spinal cord injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of the central nervous system (CNS), which in ...
Cell death is counteracted by mitophagy in HIV-productively infected astrocytes but is promoted by inflammasome activation among non-productively infected cells
(Frontiers Media SA, 2018-11)
Despite more than 30 years of extensive research efforts, a complete understanding of the neurological consequences of HIV central nervous system (CNS) infection remains elusive. HIV is not only able to establish a viral ...
Mecanismos de captação e toxicidade do metilmercúrio: Envolvimento do sistema glutamatérgico e do cálcio em fatias e mitocôndrias de ratos.
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2012-01-22)
Methylmercury (MeHg) is a highly toxic environmental contaminant that can be accumulated on several tissues, inducing cellular dysfunction on various organs, especially in the central nervous system (CNS). The mechanisms ...
Roles of calcium and Mitochondria-Associated Membranes in the development of obesity and diabetes
(UANL. Facultad de Medicina, 2016)
4′-Chlorodiazepam Protects Mitochondria in T98G Astrocyte Cell Line from Glucose Deprivation
(2017-08-01)
The translocator protein (TSPO), formerly known as the peripheral-type benzodiazepine receptor (PBR), is considered an important regulator of steroidogenesis and a potential therapeutic target in neurological disorders. ...
Mitochondrial permeability transition in neuronal damage promoted by Ca2+ and respiratory chain complex II inhibition
(Blackwell Publishing LtdOxfordInglaterra, 2004)